ARCA biopharma, Inc. (NASDAQ:ABIO) – ARCA Biopharma Inventory Features As Security Committee Recommends COVID-19 Trial To Proceed Unchanged

  • The Knowledge and Security Monitoring Committee (DSMC) has accomplished a pre-specified interim evaluation for ARCA biopharma Inc’s (NASDAQ: ABIO) ASPEN-COVID-19 Section 2b trial evaluating rNAPc2, a small recombinant protein for COVID-19.
  • Based mostly on the evaluate of roughly 75{b02bdf04de3f9bc06c998e855c65941e7d8f5cd012e86469a83340818e6b6d52} of the projected ultimate efficacy and security information, DSMC really useful finishing the trial with no modifications to the trial design. 
  • The rNAPc2 growth program has been granted FDA Quick Monitor designation. 
  • The Firm anticipates finishing the goal enrollment of 160 sufferers by year-end 2021 and reporting topline information in Q1 of 2022.
  • ASPEN-COVID-19 trial is evaluating two dose regimens of rNAPc2 versus heparin in hospitalized constructive sufferers who even have an elevated D-dimer stage. 
  • The trial’s main endpoint is the change in D-dimer stage from baseline to Day 8 relative to plain of care heparin. 
  • D-dimer is a biomarker generally used for assessing coagulation activation, which is elevated in roughly 40{b02bdf04de3f9bc06c998e855c65941e7d8f5cd012e86469a83340818e6b6d52} to 75{b02bdf04de3f9bc06c998e855c65941e7d8f5cd012e86469a83340818e6b6d52} of hospitalized COVID-19 sufferers and is related to opposed medical outcomes.  
  • Heparin is a generally used anticoagulant for COVID-19.  
  • Value Motion: ABIO shares are up 19.1{b02bdf04de3f9bc06c998e855c65941e7d8f5cd012e86469a83340818e6b6d52} at $3.12 throughout the premarket session on the final test Friday.

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